With the progress of minimally invasive surgical technology and the popularization of the concept of accelerated rehabilitation surgery, thoracic surgery is developing rapidly in the direction of minimally invasive and day-to-day surgery. However, patients after thoracic surgery still face the risk of postoperative complications, among which postoperative persistent pulmonary air leakage is still one of the most common complications of thoracic surgery, and the incidence of persistent pulmonary air leakage is as high as 10% ~26%[1,2,3,4], often bothering patients and medical staff. Persistent pulmonary air leakage refers to the pathological communication between the pulmonary parenchyma (alveoli) at the distal end of the pulmonary segment bronchi and the pleural cavity for a long time, and the clinical manifestation is pneumothorax. Persistent pulmonary air leakage causes many adverse effects on patients, significantly prolongs the postoperative tube drainage time and hospital stay, and may even cause serious complications, such as massive subcutaneous emphysema, dyspnea, lung infection, incision infection, empyema, etc., which increases the mental and economic burden of patients, seriously affects the rehabilitation of patients and the effective utilization of medical resources[5]。 The occurrence of persistent pulmonary air leakage is related to a variety of factors, including past history of pulmonary disease, advanced age, decreased pulmonary function, pleural adhesion and surgery, etc[6,7]。 Reducing the incidence of persistent pulmonary air leakage through scientific perioperative management strategies is of great significance for improving the postoperative quality of life of patients, speeding up the recovery process and reducing the medical burden.