The patient was a 37-year-old female. Because of the different iris color in both eyes since childhood, he went to the Department of Ophthalmology, Affiliated Hospital of Nantong University. Physical examination: white hair, even eyebrows, no skin abnormalities, family genetic history (his father and twin daughters all have the same performance), and family no history of close relatives marriage. Eye examination: visual acuity was 1.0 in both eyes; IOP was 15 mmHg (1 mmHg =0.133 kPa) in the right eye and 16 mmHg in the left eye; No tremor in both eyes; The corneas of both eyes are transparent, the surface of the iris of the right eye is blue-gray fine villous, with clear and radial texture, followed by dark brown, and the pupil collar structure is missing. The slit lamp retroillumination examination shows that the iris has no light transmission defect, the root of the iris in the left eye is depigmented at 3: 00, the surface of the residual iris is dark brown, with clear and radial texture (essence picture 1), and the refractive interstitium of both eyes is clear; The bottom color of the right eye is red, with a large amount of pigment loss in the retinal pigment epithelial layer, choroidal blood vessels can be seen, and no abnormalities are seen in the left fundus (Quintessential Picture 2). Coherence optical tomography angiography of the anterior segment of the eye: the vascular reflection signal of the iris of the right eye was significantly increased (Quintessential Picture 3). Clinical diagnosis: Ocular albinism in the right eye.
