2018年 · 第53卷第05期

Drug-induced gingival hypertrophy refers to the fibrous hyperplasia and volume increase of the gums caused by long-term use of certain drugs. Clinically, the three commonly used drugs related to drug-induced gingival hypertrophy include antiepileptic drugs (such as phenytoin), immunosuppressants (such as cyclosporine) and calcium channel blockers (such as nifedipine)^[1]。 Severe gingival hypertrophy can cause patients with difficulty in chewing, affect pronunciation and facial appearance, and seriously affect patients' physical and mental health. Clinically available treatments include strict oral hygiene measures, basic periodontal treatment, withdrawal or dressing change, antimicrobial therapy, and surgical treatment. Some cases have been reported that perfect basic periodontal treatment can alleviate gingival inflammation, thereby reducing or eliminating gingival hyperplasia^[2]。 A case of cyclosporine-related drug-induced gingival hypertrophy was treated in the Department of Periodontology, Guanghua School of Stomatology, Sun Yat-sen University. Through basic periodontal treatment and strict self-plaque control, good results were achieved, which are reported as follows.

Professor Li Bingqi, a famous stomatological educator in China, pioneer of modern oral mucosal diseases in China, chief scientist of oral mucosal diseases, founding chairman of the Oral Mucosal Disease Professional Committee of Chinese Stomatological Association, advanced worker of national health system, winner of Sichuan Medical and Health Lifetime Achievement Award, doctoral supervisor, and Professor Li Bingqi of West China Stomatological Hospital of Sichuan University died in Chengdu at 9: 3 on March 17, 2018 at the age of 85 due to ineffective treatment.