As human beings enter the 21st century, rapid changes and progress have occurred in various scientific fields, especially in the field of medicine. On the one hand, a large number of new technologies and new medical methods are constantly emerging; On the other hand, some new medical concepts, such as systemic medicine, translational medicine, precision medicine, integrative medicine and 4P [that is, preventive, predictive, personalized and participatory] medical models have emerged one after another, challenging traditional medical theories and concepts. These speculations and practices about medicine are promoting the progress of medicine.
In October 2016, the American Joint Committee on Cancer (AJCC) and the International Anti-Cancer Alliance jointly updated and released the 8th edition of tumor TNM staging, and published the 8th edition of the AJCC Tumor Staging Manual (referred to as the "Manual") and interpreted it in accordance with conventional practice. This edition of the guideline will be implemented on January 1, 2018. Since the first edition of the manual was published in 1977, AJCC tumor TNM staging system has been widely adopted by medical staff, researchers and tumor registration institutions in various countries after many revisions and decades of clinical application, and has become a "consensus language" suitable for staging malignant tumors in various disciplines.
Clinically, it is common that the missing tooth is not restored for a long time, which leads toThe tooth continues to erupt. In the early stage, our group used direct composite resin restoration to treat single maxillary overerupted posterior tooth with occlusal depression, and successfully obtained mandibular tooth restoration space within 6 weeks, and completed permanent all-ceramic restoration[1]。 At present, the resin transitional restoration with direct elevation was used to depress multiple overerupted posterior mandibular teeth, and enough space for maxillary three-unit fixed bridge restoration was obtained. The follow-up was carried out for 5 years, as reported below.
extranodal nasal type NK/T cell lymphoma (ENKTCL) is a subtype of non-Hodgkin's lymphoma originating from mature NK and T cells. Clinically, it is characterized by destructive lesions that tend to occur in the midline of the nose and face. In the early stage, it mainly occurs in the nose and invades the middle of the nose or face. In the later stage, it is prone to systemic dissemination and hemophagocytic syndrome. According to Ann Arbor staging, it is generally divided into stages Ⅰ ~ Ⅳ clinically. The disease can be diagnosed according to the clinical manifestations and the unique pathological manifestations of tumor cells showing vascular central infiltration, vascular destruction and coagulation necrosis. There is currently no uniform treatment plan. A case of hemophagocytic syndrome (HPS) secondary to ENKTCL ⅡB was admitted to the Department of Stomatology of the Fourth Hospital of Hebei Medical University, and the report is as follows.
The tooth continues to erupt. In the early stage, our group used direct composite resin restoration to treat single maxillary overerupted posterior tooth with occlusal depression, and successfully obtained mandibular tooth restoration space within 6 weeks, and completed permanent all-ceramic restoration[
