Chordoma is a rare, slow-growing, locally aggressive and destructive malignant bone tumor[1,2,3]。 Chordomas tend to occur in axial bones such as skull base and spine, and about 30% of them originate in skull base. Due to the characteristics of deep anatomical location, wide invasion range, complex and fragile peripheral nerves and blood vessels, insensitivity to conventional radiotherapy and easy recurrence, the diagnosis and treatment of skull base chordoma requires the cooperation of neurosurgery, otolaryngology, head and neck surgery, oral and maxillofacial surgery, plastic surgery, radiotherapy, oncology, pathology and imaging doctors. However, in clinical practice, doctors in related disciplines still have insufficient understanding of it, and diagnosis and treatment need to be standardized urgently. Skull Base Surgery Branch of China Association for the Promotion of International Medical Care Exchange, Skull Base Surgery Branch of European and American Alumni Association Physicians Association, and Neurosurgery Branch of China Association for the Promotion of International Medical Care Exchange organized the above-mentioned multidisciplinary experts with rich experience in clinical diagnosis and treatment of chordoma by reading literature, sorting out work experience, summarizing relevant research results, and repeatedly discussing and forming the following opinions for the reference of medical staff in related fields, in order to help the standardized treatment and clinical research of skull base chordoma.
