2015年 · 第50卷第01期

In the blink of an eye, we sent away our memorable 2014 and welcomed 2015.

With the progress of science and technology and the acceleration of global communication, the real world separated by thousands of rivers and mountains has gradually shrunk into a global village interconnected in the information field. No matter where they are, people live in a world full of massive data. Although human culture has evolved for thousands of years, 90% of the existing data is generated after the advent of the Internet, and more than 98% of the information worldwide is stored digitally. Today, the torrent of big data has had a huge impact on people's daily life, and all sectors of society have begun to be enthusiastic about big data. However, for the medical staff who are busy treating diseases and saving lives all day long, it seems that they have no time to care about the massive data coming to their faces and always stay out of it. In the era of big data, Eric Top, a famous American cardiologist who is a pioneer in the medical industry, is an innovation promoter who is rich in scientific literacy, dares to challenge the existing system and embraces modern technology. Not only did he practice the path, but he also wrote books and led the trend^[1]。 He believes that almost everything around us today has been digitized. However, perhaps its own deep-rooted or natural rejection of new things, the medical industry in which we are settled has never really been affected by the wave of big data. However, there is no escaping the fact that the medical industry is about to be "creatively disrupted" and disrupted. iPhone, cloud computing, 3D printing, gene sequencing, wireless sensors, supercomputers, these things that have changed our lives will once again merge to cause unprecedented "creative destruction" of medicine. The author believes that in the face of the surging wave of big data, only by being in it, studying hard, being diligent in practice, thinking further and doing better can we stand up for our main business and stand at the forefront^[2]。

In recent 20 years, dental implant has become a new subject in the rapid development of dental medicine. More and more dental implant practitioners realize that the direction, position and depth of implant have a certain accuracy and meet the requirements of restoration, so the success rate can be higher^[1,2]Therefore, the dental implant technologies of computer aided design (CAD) and computer aided mannfocture (CAM) play a driving role in the development and progress of dental implants^[3,4]。 At present, the Pioneer Drill Navigation Plate, which is widely used in clinical practice, further improves the accuracy of implantation site and direction, but there are still errors in position and direction. Full-course navigation is an advanced method based on implant simulation design, CAD-CAM surgical guide plate, and the use of corresponding guidance tools to carry out full-course controllable operation of implant surgery. The clinical results of 42 cases of dentition defects in different parts and implant surgery with dentition defects using full-course navigation technology are reported below.

Hereditary oral diseases are a special kind of oral diseases, which have unique disease categories, clinical characteristics, diagnostic criteria and pathogenic mechanisms. Systematic learning of relevant knowledge is conducive to the correct diagnosis and differential diagnosis of this kind of diseases, providing personalized treatment for patients, and promoting the mechanism research of hereditary oral diseases.

With the development of oral implant technology, immediate implant placement and provisionalization (IIPP) technology has become a hot spot in international implantology research. This paper reviews the indications of IIPP, postoperative aesthetic effect and technical progress of improving aesthetic effect.

the neck cystic metastatic squamous cell carcinoma (NCMSCC) is often misdiagnosed as branchial cleft cyst or branchial cleft carcinoma, which has been reported in the literature in recent years^[1,2,3,4,5]。 The main reasons for misdiagnosis are as follows: ① The initial clinical symptoms are similar to those of branchial cleft cyst^[1,2,3,4,5]； ② The tissue phase is the same as that of branchial cleft cancer^[6,7,8,9,10]； ③ The primary cancer is small in size or occult in site^{[11,12,13,14,15,16,17]}； ④ The understanding of branchial cleft cancer is still controversial^{[18,19,20,21,22,23,24,25,26,27,28,29,30]}。 Therefore, in order to avoid misdiagnosis, mistreatment or delayed treatment of NCMSCC, the clinical manifestations, diagnosis and differential diagnosis and treatment of NCMSCC are summarized below.

nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is a rare autosomal dominant genetic disease. At present, it is believed that it is caused by the mutation of PTCH1 gene at the autosomal 9q (22.3-q31) locus, and the incidence rate is 1/57 000 to 1/256 000. NBCCS are more common in adults, and the youngest patient reported in China is 13 years old^[1]Most abroad are over 20 years old. A 9-year-old patient with NBCCS was admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine, and the report is as follows.