2021年 · 第37卷第07期

hemostatic disorders associated intracerebral hemorrhage (HDICH) refers to intraparenchymal hemorrhage that occurs during the use of anticoagulant or antiplatelet drugs, or on the basis of hemorrhagic disorders. With the aging of the population and the widespread development of endovascular therapy, the use of antiplatelet and anticoagulant drugs is increasing, and the incidence of HDICH is also increasing^[1,2]。 It has been reported in the literature that oral anticoagulant-related ICH accounts for 25.8% of all cerebral hemorrhage^[3]。 Compared with spontaneous ICH alone, HDICH has a higher incidence of hematoma enlargement, worse functional prognosis, and higher mortality^[4,5,6]。 Its treatment involves the reversal and substitution of coagulation dysfunction, the restart of antiplatelet or anticoagulant drugs, and the surgical strategies and techniques also have their own particularities, which require multidisciplinary collaborative diagnosis and treatment. In view of this, this paper brings together domestic experts from many disciplines to formulate this guideline on the basis of reviewing relevant literature at home and abroad. [Recommended levels of this guideline: Level I should be implemented, Level IIA is appropriate to implement, Level IIB is considerable, Level III is unhelpful or harmful. Evidence levels: Level A is multicenter or multiple randomized controlled trials (RCTs), Level B is single-center single randomized controlled trials or multiple non-randomized controlled trials, Level C is expert opinions and case studies].

neurofibromatosis type 2 (NF2) is an autosomal dominant genetic disease caused by the mutation of NF2 gene on chromosome 22. It is manifested as a systemic multisystem lesion syndrome, mainly including neurological lesions, ophthalmic lesions and skin lesions^[1]。 Among them, NF2-related multiple tumors of the nervous system are the most serious lesions and the main cause of death and disability. The disease is very complex, clinically incurable and sustainable. Multidisciplinary cooperation is required in treatment. After fully assessing the patient's overall state, tumor load, treatment benefits and treatment risks, an individualized treatment plan is formulated, and surgery, radiosurgery, drugs and neurological reconstruction are reasonably used to treat, so as to prolong the patient's survival, protect and maintain important neurological functions, and improve the patient's quality of life. Initiated by the Neurotumor Professional Committee of China Anti-Cancer Association, in conjunction with experts from neurosurgery, otolaryngology, dermatology, medical oncology, radiosurgery and imaging departments of many medical institutions across the country, the Chinese Expert Consensus on Multidisciplinary Collaborative Diagnosis and Treatment Strategies for Neurosystem Tumors of Type 2 Neurofibromatosis was jointly written, aiming at promoting the standardized diagnosis and treatment of NF2 and improving the treatment level of NF2.