The patient was a 17-year-old female. Because of blurred vision in both eyes for 1 month, he went to the Department of Fundus Medicine, Optometry Hospital affiliated to Wenzhou Medical University. Deny history of hypertension, diabetes, drug and food allergies. Eye examination: corrected visual acuity was 0.05 for the right eye and 0.4 for the left eye; IOP was 11.6 mmHg (1 mmHg =0.133 kPa) in the right eye and 10.3 mmHg in the left eye; There is no conjunctiva congestion in both eyes, the cornea is transparent, the anterior chamber is clear, the depth is normal, the pupil is round, the light response is sensitive, and the lens is transparent; The tumor body can be seen at the end of the thick nourishing vessel below the retina of the right eye, and the lower retina is detached (Quintessential Picture 1A); Tumor body and hyperplasia traction can be seen at the end of the thick nourishing vessel above the temporal side of the left eye retina, and hard exudation can be seen in the macular area (Quintessential Picture 1B). Fluorescein fundus angiography examination is shown in Essence Pictures 2 and 3. Clinical diagnosis: binocular Von Hippel-Lindau syndrome.
