The patient was a 24-year-old female. Because of grinding pain in both eyes and blurred vision for 5 days, he went to Hebei Eye Hospital. He had been myopic in both eyes for 12 years and wore contact lenses intermittently. Eye examination: visual acuity was 0.12 for the right eye and 0.1 for the left eye; IOP was 15.0 mmHg (1 mmHg =0.133 kPa) in the right eye and 14.0 mmHg in the left eye; The conjunctiva of the right eye was mixed congested, with an inverted triangular epithelial defect of about 2 mm ×3 mm in the central cornea, mild edema of the corneal epithelium in other parts, vague intraepithelial microvesicle-like changes, and no edema of the corneal stroma; The conjunctiva of the left eye is mildly congested, the corneal epithelium is rough, and a large number of microvesicle-like changes with basically the same shape and size can be seen in the corneal epithelium in the central area, with a range of about 6 mm ×7 mm. The corneal fluorescein staining is positive, the corneal epithelium in other parts is smooth, and there is no edema in the corneal stroma (Essence Picture 1); The anterior chamber of both eyes was moderately deep, the aqueous humor was clear, the pupil was round, about 3 mm in diameter, and the response to light was normal. Clinical diagnosis: binocular Meesmann corneal dystrophy.