2017年 · 第53卷第02期

This issue focuses on the clinical and basic research of glaucoma. The responsible editorial committee responsible for the planning, composition and review of this issue is Professor Sun Xinghuai.

The optic nerve tissue of human body is located in two pressure cavities, the intraocular cavity and the intracranial cavity, respectively. The intraocular pressure is slightly higher than the intracranial pressure, and the pressure difference between intraocular pressure and intracranial pressure crosses the sieve plate, forming a pressure gradient along the optic nerve, called the oculocranial pressure gradient, that is, the pressure difference across the sieve plate. In recent years, the research on the role of cranial pressure gradient in the mechanism of optic nerve injury in glaucoma has attracted more and more attention of glaucoma scholars at home and abroad, and has become a hot issue in the international glaucoma academic circle. Chinese scholars have carried out a lot of work in this field and achieved remarkable results.

The patient was a 60-year-old male. He was seen in Tianjin Eye Hospital due to swelling of his right eye with visual acuity decrease for 4 months. There were no obvious abnormalities in the whole body examination. Eye examination: visual acuity was 0.01 for the right eye and 0.6 for the left eye; The appearance of the right eye is normal, the eyelid is not red or swollen, and the eye surface and anterior segment are shownQuintessence Picture 1, the fundus of the eye can not see; The lens of the left eye was slightly opaque, and no obvious abnormalities were found in the anterior segment and fundus of the rest of the eye. The patient underwent enucleation of the right eye. Histopathological diagnosis: right eye ciliary body choroidal melanoma (mixed cell type predominantly spindle cells) (Quintessence Picture 2）。

Surgery is one of the important methods to treat glaucoma in children. Glaucoma surgery in children is more challenging than surgery in adults, with a higher rate of failure and complications than in adults. Since the first surgery is often an important time for successful treatment, it is crucial to choose the best surgical method^[1]。 The choice of surgical methods for childhood glaucoma is influenced by factors such as the type, severity, age of onset or symptoms of childhood glaucoma and eye conditions^[1,2,3,4]。 Pediatric glaucoma surgery mainly includes anterior chamber angle surgery (anterior chamber goniotomy, traditional or total trabeculotomy), trabeculectomy, combined trabeculotomy-trabeculectomy surgery, aqueous humor drainage valve implantation, ciliary body photocoagulation surgery, lens surgery, etc. This lecture focuses on trabeculotomy, trabeculectomy, and combined trabeculotomy-trabeculectomy surgery.

Graves disease, also known as toxic diffuse goiter, is an autoimmune thyroid disease and a common cause of hyperthyroidism (hyperthyroidism). Graves' ophthalmopathy (GO) is the most common extrathyroid manifestation of Graves' disease. What we currently call thyroid associated ophthalmopathy (TAO) in clinical practice can occur in patients with normal thyroid function and Hashimoto's thyroiditis in addition to patients with Graves disease. The term GO used in this article only refers to TAO that occurs in Graves disease.