The Determination of 22 cases in normal children by radioimmunoassay (RIA), the content of blood plasma endothelin (84.13±26.16pg/ml) ±s, 15 cases with acute glomerulonephritis (77.63±34.11pg/ml), 10 cases with simple nephrosis (140.03±51.80pg/ml), 11 cases with chronic glomerulonephritis in adult (223.32±68.09pg/ml). 26 cases in the gronp of normal adult, the content of blood plasma endothelin (88.43±26.27pg/ml), the comparison between the gronps of normal children and normal adult P>0.05.
T-lymphocyte subset (CD4/CD8) and ConA activated suppresser (Ts) cell activity was measured in 24 children with idiopathic syndrom (INS). Six Patients was only treated by using Cimetidine (CMD) in two weeks. The result showed INS in the activity stage their CD4/CD8 is lower and Ts cell activity is higher than normal children's. CD4/CD8 and Ts activity abnormality can be corrected by using CMD in two weeks. But urinary protein was not affected at same time. We thought that the cellar immunity abnormality was not primary agent in the pathogensis of INS.
±s, 15 cases with acute glomerulonephritis (77.63±34.11pg/ml), 10 cases with simple nephrosis (140.03±51.80pg/ml), 11 cases with chronic glomerulonephritis in adult (223.32±68.09pg/ml). 26 cases in the gronp of normal adult, the content of blood plasma endothelin (88.43±26.27pg/ml), the comparison between the gronps of normal children and normal adult P>0.05.
