Radiotherapy is one of the main treatments for penile cancer. Radiotherapy for early penile cancer can preserve the penis and make the lesion obtain LC, while radiotherapy for advanced penile cancer can play a palliative or symptomatic effect. Because the root of the penis attached to the inferior pubic branch, the ischial branch and the urogenital diaphragm are relatively fixed, the rest part is free and has a large range of mobility, which brings great difficulties to the fixation of the organs of radiotherapy for penile cancer and the protection of the sensitive organs testis. Liu Yajun et al.[1]The liquid paraffin is used to make a homemade penis fixation device, but the foam module is difficult to reflect the true size of the patient's penis. The fixed box is easy to obtain materials, has low cost, does not have discomfort and inconvenience to patients due to water temperature and fluid compared with water box irradiation, and is simple to manufacture, and can also be made individually according to individual differences of patients.