2015年 · 第24卷第05期

In recent years, the application of EB-PBI in breast-preserving therapy has received extensive attention. Target determination is a key link in EB-PBI, which is closely related to local tumor control, adverse reaction occurrence and breast cosmetic effect^[1]。 The study showed that the differences among delineators were influenced by the development of delineator standards, delineator training, seroma visibility, and the number of metal clips for marking the surgical cavity^[2,3]However, it is not clear that the difference between delineators when delineating the target area of the surgical cavity based on seroma, metal clip or seroma combined with metal clip is appropriate in the case of appropriate seroma visibility and appropriate number of metal clips. Therefore, based on 4DCT simulated localization scan, this study investigated the effect of different reference materials on the differences between delineators when the seroma visibility was ≥3 points and the labeled metal clips were ≥5.

On June 26-28, 2015, the "First Academic Conference of Northern China Cancer Radiotherapy Cooperation Group and Individualized Treatment Class of Esophageal Cancer" sponsored by the Northern China Cancer Radiotherapy Cooperation Group (hereinafter referred to as the Cooperation Group) Committee and undertaken by Shandong Cancer Hospital was held in Zibo, Shandong Province. Professor Yu Jinming, academician of Chinese Academy of Engineering, president of Shandong Cancer Hospital and honorary chairman of the cooperation group, and Professor Wang Ping, president of Tianjin Medical University Cancer Hospital and honorary chairman of the cooperation group attended the opening ceremony and gave academic presentations. The meeting was presided over by Professor Li Baosheng, rotating chairman of the cooperation group and vice president of Shandong Cancer Hospital. Nearly 600 oncology radiotherapy professional colleagues from 10 northern provinces attended the conference.

OAR delineation in the course of radiotherapy has been time-consuming, especially for the complex shape of nasopharyngeal tumors, the wide range of treatment and the close proximity of many OARs^[1,2]。 The author uses the Atlas Based segmentation function in Raystation v3.99.0.7 to study the feasibility of automatically delineating OAR in nasopharyngeal carcinoma.

In recent years, with breast imaging technology widely used in early breast cancer diagnosis, the proportion of patients undergoing breast-conserving surgery has increased greatly^[1]。 Adjuvant radiotherapy after breast-conserving surgery has become the standard treatment, and this method has shown good results in both LC rate and OS rate^[2,3,4]。 However, the whole course of conventional radiotherapy takes 5 to 6 weeks, which makes it difficult for some patients to receive radiotherapy, and some patients therefore choose total mastectomy^[5]。 Accelerated partial breast irradiation provides a new option for patients. This technique can significantly shorten the total treatment time. Accelerated partial breast irradiation provides a good option for those patients who cannot leave work for long periods of time, or who come from out of town for radiotherapy, and can avoid some patients undergoing unnecessary total mastectomy surgery. There are many types of accelerated partial breast irradiation therapy techniques, such as intraoperative radiotherapy, balloon therapy, external irradiation therapy, and multi-channel implant brachytherapy^[6,7,8]。 This paper mainly studies the application of multi-channel implantation brachytherapy to accelerate partial breast irradiation, including clinical indications, comparison of different implantation methods, and experience and skills to achieve good implantation results.

High-grade glioma (WHO grade III and IV glioma) is the most common intracranial malignant tumor in adults, accounting for about 35% to 45% of primary intracranial malignant tumors. The tumor did not have an intact envelope, showed invasive growth, and the boundary with normal brain tissue was unclear. Radiotherapy and chemotherapy are important adjuvant treatments, which can significantly improve the survival of patients^[1,2,3]。 With the emergence of simultaneous chemoradiotherapy as a standard treatment mode and the advent of the era of precise radiotherapy, there are still great controversies in recent years about the exposure range, postoperative start time of radiotherapy, radiotherapy dose and segmentation mode. This article summarizes these issues as follows.

Heavy ions, in short, are more than alpha particles (⁴H) heavy ions (e.g.¹²C,²²Ne,⁴⁵Ca et al.), which has attracted much attention in the oncology radiotherapy community because of its dual advantages in physical dose distribution and biology after acceleration. Due to the influence of experimental facilities, basic and clinical data, there is still a lack of comprehensive understanding of the radiobiological effects of heavy ions, including the killing effect of tumor cells, the influence on tumor angiogenesis and metastasis, and the induction of second tumor. The basic biological characteristics of heavy ions (mainly carbon ions) and related biological research progress are reviewed.