Volume 95  ·   Issue 04  ·  1982

207 of 210 kala azar cases occurred in North-west China in 1967-1970 had localized nontender enlarged lymph glands, 50 of them were admitted to a local hospital. Authors reviewed their clinical symptoms and signs, laboratory findings, diagnosis, treatment and control. The epidemiologic survey in the endemic area revealed that Phlebotomus major wui is the main transmitting sandfly vector. The importance of Mongolian gerbil Phlebomys opimus as a wild animal reservoir host of leishmaniasis is mentioned and discussed.

In this paper a new curved combined 4-ring incision is introduced. It gives satisfactory exposure for bilateral herniorrhaphy.

92 cases of intussusception in adults are presented with emphasis on X-ray diagnosis and nonoperative treatment by air inflation into the colon at 60-120 mm Hg. The advantages and limitations of this treatment are discussed.

35,529 cases examined fibergastroscopically are collected from 52 domestic papers for calculation of conditional and prior probability values of 4 classes of diagnostic results. According to the program, these values are taken as computer input. When a new patient is diagnosed, the output is in the form of probability values of various suspected disorders. The maximum probability value is taken as the result of computer-aided diagnosis (CAD). The CAD accuracy of 58 gastric cancer cases confirmed pathologically is 87.93% and reliability 89.47%. Total agreement rate of 132 cases in 4 classes is 81.82%. CAD is promising in differential diagnosis of gastric cancer. Statistical analysis shows. that the ac- curacy and reliability of CAD are Superior to barium gastroenterography and experienced physician diagnosis.

The SRBC-receptor may either be situated loosely outside the T cell surface membrane, or may be a part of a protein anchoring upon or penetrating the surface membrane which can be easily removed or recombined. Isolation of the SRBC-receptor by affinity chromatography greatly short.ens the time needed for isolation from more than a week to within a working day. Both time and reagents are saved and the columns can be used repeatedly. The receptor is purified 240 times and only 1 component is obtained by us whereas Chisari, Owen and Fanger and our previous experiments all showed SRBC-receptors of 3-4 components. The SRBC-receptor is not merely a characteristic T cell marker, its role in T cell activation by SRBC is of interest for further investigation. The authors think that the study of the SRBC-receptor is of importance in cellular immunology both theoretically and practically.

Piperaquine, 1,3-bis [1-(7-chloro-4'quinolyl)-4'-piperazinyl]-propane, belonging to the 4-aminoquinolines, is a synthesized drug with a chemical structure identical with 13228 RP. In Hainan Island, Guangdong province, 43 cases of Plasmodium falciparum were treated with the drug at a total dose of l.8 gm base for each adult on 2 consecutive days. The fever and asexual blood parasites cleared up within 72 hours after administration, showing the drug to be an effective schizonticide. In order to observe the long-acting suppressive effect of the drug, field trials were carried out on a relatively large scale during the contagious seasons (from June through September) in 3 consecutive years from 1972 to 1974 in a Hainan Island county. In several villages of this county every person took 2 tablets (300 mg piperaquine base each) monthly from June through September, 1973. The malaria incidence in the treated group lowered steadily from 2.8% (in June) to 1.4% (in September), whereas that of the non-treated control group in the same village was 5.8%-10.3%. In the trial of 1974 the rate of parasite carriers was reduced from 33.8% before administration to 10.6% after the last administration. The actual period of protection afforded by the drug was about 20 days The side-effects, such as headache, listlessness and dizziness were mild. No serious toxic symptoms were noted.

Internal iliac artery ligation is used for controlling hemorrhage during suprapubic prostatectomy in 110 cases. Of these, 2 were over 80 years old, 18 had hypertensive cardiovascular disease and 16 showed myocardial insufficiency. All withstood the operation uneventfully. No evidence of ischemia was noted in the pelvic organs. The amount of blood loss was estimated during and after operation in 34 cases, compared to other prostatectomy procedures, blood loss is minimal as is the risk of hemorrhage. Since it is not necessary to suture the vesical neck as in the Hryntschak technic, the incidence of urethral stricture can be lowered. Hence it is a suitable procedure for suprapubic prostatectomy.

An analysis is made of 3 choriocarcinoma autopsies and 2 malignant hydatidiform moles. A single cerebral metastatic tumor was found in 12 and multiple metastatic tumors in 20, of which 17 were bilateral. Three cases had cerebral embolisms. The preferred sites of cerebral metastasis were the parietal and occipital lobes, especially at the junction of the parietal, occipital and temporal lobes. The pathologic features of the cerebral metasitatic choriocarcinomas showed 4 different types: Type I (tumor mass) 10; Type II (hematoma) 15; Type III (embolic) 3; Type IV (mixed) 7. There were 16 with massive hemorrhage, 6 rupturing the cerebral ventricles.

Chronic atrophic gastritis (CAG) seen in Shanghai has its own characteristics quite different from those reported abroad. It merits our attention for further exploration of CAG etiology, pathogenesis, diagnosis and treatment, especially its relation to gastric carcinoma, a high incidence disease in Shanghai.