2016年 · 第50卷第10期

Intracranial syphilis gum is a rare late neurological manifestation involving the central nervous system after infection with Treponema pallidum, and it is mostly diagnosed with intracranial space occupation. Because of the lack of understanding of its imaging manifestations, it often leads to preoperative misdiagnosis. Treatment with penicillin G can heal most of the syphilis gum, and only a few patients with intracranial hypertensive crisis or resistance to penicillin need surgical resection of the lesion. Therefore, an accurate diagnosis of this disease can reduce the risk of unnecessary surgery. At present, there are few literature reports on the imaging manifestations of cerebral syphilis gum-like swelling, but most of them are case reports^[1,2]。 The author collected 5 cases of gum-like swelling of cerebral syphilis confirmed by operation and pathology, and analyzed their imaging manifestations in order to improve the understanding of this disease.

phase contrast MR (PC MR) is a new blood flow measurement method, which can accurately obtain the information of blood flow velocity at a certain time interval in the cardiac cycle^[1,2,3,4]。 The flow velocity data measured by PC MR method can be further connected and interpolated to obtain the corresponding time-flow velocity curve. However, the interpolation processing can't effectively summarize the relationship between time variables and blood flow variables in the time-flow velocity curve, and it is not conducive to further identifying and processing the characteristics of time-flow velocity curve by computer. Therefore, we try to process the flow velocity data of the aorta measured by PC MR method by polynomial curve fitting method, in order to obtain the approximate function expression of flow velocity and time. On this basis, the fitted function is verified by combining the interpolation of original data and ultrasound images, so as to obtain the best function parameters and expression.